International Journal of Pharma and Bio Sciences EVALUATION OF ANTIBACTERIAL ACTIVITY OF CUSCUTA REFLEXA AND ABUTILON INDICUM

There is a currently worldwide upsurge in the use of herbal preparations and active ingredients of medicinal plant in health care. This is particularly true in the rural areas of Asian countries where herbal medicines are the only choice for treating human ailments. Present study reveals the difference in the antimicrobial activity pattern extracts of Cuscuta reflexa and Abutilon indicum in ethanol, chloroform, ethyl acetate and aqueous solvents against the pathogenic organisms E.coli (ATCC-25922), Staphylococcus aureus (ATCC-25923), Pseudomonas aeruginosa (ATCC-27853), Proteus vulgaris(ATCC 6380), Salmonella paratyphi(ATCC-9150), Shigella sonnei(ATCC-25931), Salmonella typhimurium(ATCC-25241), and Klebsiella pneumonia(ATCC-27736). Among all the extracts Ethanol and Chloroform showed greater activity with a zone of inhibition ranging from 6mm to 17mm. Ethanol extract of Cuscuta reflexa exhibited better antibacterial activity with IC50 value range 16.93-55mg/ml when compared with ethanol extract Abutilon indicum. The results of crude extracts were compared with standard Antibiotic Chloramphenicol(30 mcg). AYESHA MATEEN Central Research Institute of Unani Medicine, Opp, E.S.I. Hospital, Erragadda, Hyderabad – 500038, India